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DIRECTORATE-GENERAL

INSPECTION
competent for all inspection and control activities

INDUSTRY DIVISION

INSPECTIONS

GMPGood Manufacturing Practices inspections

 

GCPGood Clinical Practices inspections

of which

 

GCPGood Clinical Practices inspections medicines

 

GCPGood Clinical Practices inspections medical devices

 

pharmacovigilance inspections

inspections human tissue material

inspections of manufacturers of medical devices

ADVISORY COMMISSION

applications for variations submitted to the Advisory Commission

 

RAPID ALERT SYSTEM

rapid alerts of quality of which

class 1

class 2

class 3

fraud/counterfeit

concerning medicines for human use

concerning medicines for veterinary use

concerning raw materials

concerning IMPsInvestigational Medicinal Product - a medicinal product for research

ANALYSIS OF PRODUCTS ON THE MARKET

medicines

preparations

raw materials

products seized

DISTRIBUTION DIVISION

INSPECTIONS

inspections on advertising for medicines

inspection on advertising for medical devices

GDPGood Distribution Practices inspections of medicines

 

GDPGood Distribution Practices inspections of medicines for obtaining or amending a WDAWholesaler’s Distribution Authorisation

inspections of the distribution of medical devices, of which

thematic inspections

CHECKS ON ADVERTISING AND OTHER PROMOTIONAL ACTIVITIES FOR MEDICINES AND HEALTH PRODUCTS

investigations on medicines

investigations on advertising for medical devices

investigations on the distribution of medical devices

QUESTIONS ABOUT MEDICINES AND HEALTH PRODUCTS

questions about medicines

questions about medical devices

questions about advertising for medical devices

ACCREDITATION NUMBER FOR RESPONSIBLE QUALIFIED PERSONS

accreditation numbers awarded to persons responsible for information

changes relating to persons responsible for information

TrendTrend

In 2018 there was a strong increase in the number of requests via the e-mailbox of the distribution department, including, among others, requests about the implementation of the Falsified Medicines Directive and Brexit.

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In 2018, the distribution department started to report systematically to the pharmaceutical industry regarding warnings of falsified medicines that are discovered in the European Union or elsewhere in the world. The sector has also been updated regarding stolen medicines to increase vigilance and to reduce the risk of stolen medicines being re-introduced into the local circuit. By sending documents such as inspection reports via an electronic path, the use of paper is reduced, as is transmission time of documents. The archiving of all documents related to inspections and approvals of RIPsResponsible for information and publicity is done electronically. Thematic actions performed in 2018 such as temperature control of approved rooms for the storage of medicines and for the storage of medicines in transit zones. Inspections of the transfer of medical samples were increased and reinforced the presence of the FAMHPFederal Agency for Medicines and Health Products in the field.

DISPENSING DIVISION

INSPECTIONS

retail pharmacies

TrendTrend

In 2018, there was an increase in the number of inspections of pharmacies open to the general public.

hospital pharmacies

including

for medicines

for medical devices

medicinal stocks at veterinarians

ICON-AFMPS-2018-BLACK-trend-downTrend

In 2018, there was a reduction in the number of inspections of medicinal stocks at veterinarians.

SANITEL-MED
0
controls performed at veterinarians
5.0 %
non-conformities, followed by a reminder of the legal obligation of encoding in SANITEL-MED
Critical antibiotics and practices related to food producers

controlled depots of which
 

depots no longer used critical antibiotics

depots used critical antibiotics in line with the legislation (samples, antibiogram)

medicinal stocks at healthcare professionals

AUTHORISATIONS DIVISION

HORMONES AND ANTIBIOTICS

new licences

renewals

letters of no objection (import certificates)

extensions/amendments of authorisations

NARCOTICS AND PSYCHOTROPIC SUBSTANCES

Activity licences

0
new annual activity licences
0
amendments of annual licences
0
renewals of annual licences

Licences for import and export

0
licences for import and export
0
inspections of licences for import and export
0
inspections of activity licences

Narcotics order forms

0
narcotics order forms (per 100 forms)
0

letters of no objection (import certificates)

0

authorisations end user (before “small quantities”)

PRECURSORS

0
new activity licences
0
import licences
0
export licences
0
suspicious orders and transactions

MANUFACTURING AND DISTRIBUTION AUTHORISATIONS

0
fabrication licences
0
copies of fabrication licences
0
distribution licences
0
copies of distribution licences
0
registrations APIActive Pharmaceutical Ingredient – active substance or ingredient in medicines
0
certificates of GMPGood Manufacturing Practices
0
copies of GMPGood Manufacturing Practices-certificates
0
certificates GDPGood Distribution Practices
0
copy of GDPGood Distribution Practices-certificate
0
export declarations
0
declarations of toll manufacturing activity
0
registrations broker
0
quarterly declarations fabrication/distribution IMPInvestigational Medicinal Product - a medicinal product for research
0
legalise of documents for industry (except CPPCertificate of Pharmaceutical Product – Product-specific certificates)

HUMAN TISSUE MATERIAL AND BLOOD INSTITUTIONS

0
preliminary accreditations MLM-MCHHuman tissue material organisations
0
accreditations for MLM-MCHHuman tissue material organisations

PHARMACIES

0
new applications for the Commission for establishment of retail pharmacies
0
registration forms registry of pharmacies
0
recognitions of pharmacists-clinical biologists

MEDICAL DEVICES DIVISION

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In September 2018, the Medical Devices department was established. The numbers for 2018 were still being included in the numbers of the other departments of DG Inspection. From 2019 on, the Department of Medical Devices will maintain separate reporting.

SPECIAL INVESTIGATION UNIT

0
administrative and judicial investigations closed of which
0 %
assistance to public prosecutors
0
investigations into non-compliant medical devices closed
0
investigations into abortive drugs

Number of postal packages inspected

TrendTrend

There is still an increase in the number of seized packages with illegal medicines. For each seizure, the FAMHPFederal Agency for Medicines and Health Products notifies the citizen of the risks they are taking for their health and of the applicable administrative and legal procedures.

The FAMHPFederal Agency for Medicines and Health Products works together closely with the justice department, the police and other federal agencies in the very high number of controls of cannabis shops.

 

The number of examinations of abortion drugs has increased. Irrespective of the action of SIUSpecial Investigation Unit for the investigation itself, the affected parties are always referred to the healthcare professionals to ensure adequate medical and psychological follow-up.

On an international level, the unit is very active in various WHO working groups to combat drugs criminality, including:

  • the task force combating internet criminality,
  • the task force charged with developing and promoting materials and supporting documents to increase the capacity of the agencies involved and thus detect unreliable, illegal and falsified medicines and prevent them,
  • the task force developing effective communication media and prevention campaigns for those medicines that do not fulfil the standards and are falsified.

 

The SIUSpecial Investigation Unit supported various university projects, including studying the internet criminality problem and developing a ​​technique to quickly identify illegal products.

 

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